Three-dimensional volumetric analysis and reconstruction of amygdala and hippocampal head, body and tail.
Identifieur interne : 002424 ( Main/Exploration ); précédent : 002423; suivant : 002425Three-dimensional volumetric analysis and reconstruction of amygdala and hippocampal head, body and tail.
Auteurs : Nikolai V. Malykhin [Canada] ; Thomas P. Bouchard ; Catherine J. Ogilvie ; Nicholas J. Coupland ; Peter Seres ; Richard CamicioliSource :
- Psychiatry research [ 0165-1781 ] ; 2007.
English descriptors
- KwdEn :
- Adult, Aged, Amygdala (anatomy & histology), Amygdala (pathology), Control Groups, Depressive Disorder, Major (diagnosis), Depressive Disorder, Major (pathology), Female, Functional Laterality, Hippocampus (anatomy & histology), Hippocampus (pathology), Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional (methods), Imaging, Three-Dimensional (statistics & numerical data), Magnetic Resonance Imaging (methods), Magnetic Resonance Imaging (statistics & numerical data), Male, Parkinson Disease (diagnosis), Parkinson Disease (pathology), Reproducibility of Results.
- MESH :
- anatomy & histology : Amygdala, Hippocampus.
- diagnosis : Depressive Disorder, Major, Parkinson Disease.
- methods : Imaging, Three-Dimensional, Magnetic Resonance Imaging.
- pathology : Amygdala, Depressive Disorder, Major, Hippocampus, Parkinson Disease.
- statistics & numerical data : Imaging, Three-Dimensional, Magnetic Resonance Imaging.
- Adult, Aged, Control Groups, Female, Functional Laterality, Humans, Image Processing, Computer-Assisted, Male, Reproducibility of Results.
Abstract
Volumetric changes in the amygdala and hippocampus are relevant to many disorders, but their close proximity makes it difficult to separate these structures by magnetic resonance imaging, leading many volumetric protocols to exclude problematic slices from analysis, or to analyze the amygdalo-hippocampal complex conjointly. The hippocampus tail is also often excluded, because of the difficulty in separating it from the thalamus. We have developed a reliable protocol for volumetric analysis and 3-D reconstruction of the amygdala and hippocampus (as a whole and in its anatomical parts). Twenty volunteers from clinical and healthy populations were recruited. T1-weighted images were acquired at 1.5 Tesla with native spatial resolution of 1.5 mm x 1.0 mm x 1.0 mm. Volumetric analyses were performed blind to diagnosis, using the interactive software package DISPLAY. Inter-rater (intrarater) intraclass correlations for the method were: 0.95 (0.88) for hippocampus tail, 0.83 (0.93) for hippocampus body, 0.95 (0.92) for hippocampus head, 0.96 (0.86) for total hippocampus and 0.86 (0.94) for amygdala. Volumes (mean+/-S.D.) corrected for intracranial volume for this mixed group were for the hippocampal tail: 0.325+/-0.087 cm(3); hippocampal body: 0.662+/-0.120 cm(3); hippocampal head: 1.23+/-0.174 cm(3); total hippocampus: 2.218+/-0.217 cm(3), and amygdala: 0.808+/-0.185 cm(3). In conclusion, the study demonstrates that the amygdala and hippocampal parts can be quantified reliably.
DOI: 10.1016/j.pscychresns.2006.11.011
PubMed: 17493789
Affiliations:
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Bouchard</name></author><author><name sortKey="Ogilvie, Catherine J" sort="Ogilvie, Catherine J" uniqKey="Ogilvie C" first="Catherine J" last="Ogilvie">Catherine J. Ogilvie</name></author><author><name sortKey="Coupland, Nicholas J" sort="Coupland, Nicholas J" uniqKey="Coupland N" first="Nicholas J" last="Coupland">Nicholas J. Coupland</name></author><author><name sortKey="Seres, Peter" sort="Seres, Peter" uniqKey="Seres P" first="Peter" last="Seres">Peter Seres</name></author><author><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="RBID">pubmed:17493789</idno><idno type="pmid">17493789</idno><idno type="doi">10.1016/j.pscychresns.2006.11.011</idno><idno type="wicri:Area/PubMed/Corpus">001056</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001056</idno><idno type="wicri:Area/PubMed/Curation">001056</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001056</idno><idno type="wicri:Area/PubMed/Checkpoint">001056</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001056</idno><idno type="wicri:Area/Ncbi/Merge">000767</idno><idno type="wicri:Area/Ncbi/Curation">000767</idno><idno type="wicri:Area/Ncbi/Checkpoint">000767</idno><idno type="wicri:doubleKey">0165-1781:2007:Malykhin N:three:dimensional:volumetric</idno><idno type="wicri:Area/Main/Merge">002643</idno><idno type="wicri:Area/Main/Curation">002424</idno><idno type="wicri:Area/Main/Exploration">002424</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Three-dimensional volumetric analysis and reconstruction of amygdala and hippocampal head, body and tail.</title><author><name sortKey="Malykhin, Nikolai V" sort="Malykhin, Nikolai V" uniqKey="Malykhin N" first="Nikolai V" last="Malykhin">Nikolai V. Malykhin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, University of Alberta, Walter MacKenzie Centre, 8440-112 Street, Edmonton, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, University of Alberta, Walter MacKenzie Centre, 8440-112 Street, Edmonton, Alberta</wicri:regionArea><wicri:noRegion>Alberta</wicri:noRegion></affiliation></author><author><name sortKey="Bouchard, Thomas P" sort="Bouchard, Thomas P" uniqKey="Bouchard T" first="Thomas P" last="Bouchard">Thomas P. Bouchard</name></author><author><name sortKey="Ogilvie, Catherine J" sort="Ogilvie, Catherine J" uniqKey="Ogilvie C" first="Catherine J" last="Ogilvie">Catherine J. Ogilvie</name></author><author><name sortKey="Coupland, Nicholas J" sort="Coupland, Nicholas J" uniqKey="Coupland N" first="Nicholas J" last="Coupland">Nicholas J. Coupland</name></author><author><name sortKey="Seres, Peter" sort="Seres, Peter" uniqKey="Seres P" first="Peter" last="Seres">Peter Seres</name></author><author><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name></author></analytic><series><title level="j">Psychiatry research</title><idno type="ISSN">0165-1781</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Amygdala (anatomy & histology)</term><term>Amygdala (pathology)</term><term>Control Groups</term><term>Depressive Disorder, Major (diagnosis)</term><term>Depressive Disorder, Major (pathology)</term><term>Female</term><term>Functional Laterality</term><term>Hippocampus (anatomy & histology)</term><term>Hippocampus (pathology)</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Imaging, Three-Dimensional (methods)</term><term>Imaging, Three-Dimensional (statistics & numerical data)</term><term>Magnetic Resonance Imaging (methods)</term><term>Magnetic Resonance Imaging (statistics & numerical data)</term><term>Male</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (pathology)</term><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" qualifier="anatomy & histology" xml:lang="en"><term>Amygdala</term><term>Hippocampus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Depressive Disorder, Major</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Imaging, Three-Dimensional</term><term>Magnetic Resonance Imaging</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Amygdala</term><term>Depressive Disorder, Major</term><term>Hippocampus</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Imaging, Three-Dimensional</term><term>Magnetic Resonance Imaging</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Control Groups</term><term>Female</term><term>Functional Laterality</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Male</term><term>Reproducibility of Results</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Volumetric changes in the amygdala and hippocampus are relevant to many disorders, but their close proximity makes it difficult to separate these structures by magnetic resonance imaging, leading many volumetric protocols to exclude problematic slices from analysis, or to analyze the amygdalo-hippocampal complex conjointly. The hippocampus tail is also often excluded, because of the difficulty in separating it from the thalamus. We have developed a reliable protocol for volumetric analysis and 3-D reconstruction of the amygdala and hippocampus (as a whole and in its anatomical parts). Twenty volunteers from clinical and healthy populations were recruited. T1-weighted images were acquired at 1.5 Tesla with native spatial resolution of 1.5 mm x 1.0 mm x 1.0 mm. Volumetric analyses were performed blind to diagnosis, using the interactive software package DISPLAY. Inter-rater (intrarater) intraclass correlations for the method were: 0.95 (0.88) for hippocampus tail, 0.83 (0.93) for hippocampus body, 0.95 (0.92) for hippocampus head, 0.96 (0.86) for total hippocampus and 0.86 (0.94) for amygdala. Volumes (mean+/-S.D.) corrected for intracranial volume for this mixed group were for the hippocampal tail: 0.325+/-0.087 cm(3); hippocampal body: 0.662+/-0.120 cm(3); hippocampal head: 1.23+/-0.174 cm(3); total hippocampus: 2.218+/-0.217 cm(3), and amygdala: 0.808+/-0.185 cm(3). In conclusion, the study demonstrates that the amygdala and hippocampal parts can be quantified reliably.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Bouchard, Thomas P" sort="Bouchard, Thomas P" uniqKey="Bouchard T" first="Thomas P" last="Bouchard">Thomas P. Bouchard</name><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name><name sortKey="Coupland, Nicholas J" sort="Coupland, Nicholas J" uniqKey="Coupland N" first="Nicholas J" last="Coupland">Nicholas J. Coupland</name><name sortKey="Ogilvie, Catherine J" sort="Ogilvie, Catherine J" uniqKey="Ogilvie C" first="Catherine J" last="Ogilvie">Catherine J. Ogilvie</name><name sortKey="Seres, Peter" sort="Seres, Peter" uniqKey="Seres P" first="Peter" last="Seres">Peter Seres</name></noCountry><country name="Canada"><noRegion><name sortKey="Malykhin, Nikolai V" sort="Malykhin, Nikolai V" uniqKey="Malykhin N" first="Nikolai V" last="Malykhin">Nikolai V. Malykhin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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